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Quercetin Down-regulates IL-6/STAT-3 Signals to Induce Mitochondrial-mediated Apoptosis in a Nonsmall- cell Lung-cancer Cell Line, A549.

Authors
  • Mukherjee, Avinaba
  • Khuda-Bukhsh, Anisur Rahman
Type
Published Article
Journal
Journal of pharmacopuncture
Publication Date
Mar 01, 2015
Volume
18
Issue
1
Pages
19–26
Identifiers
DOI: 10.3831/KPI.2015.18.002
PMID: 25830055
Source
Medline
Keywords
License
Unknown

Abstract

Overall, the finding of this study indicates that a quercetin induced anti-inflammatory pathway in A549 cells appeared to make a significant contribution towards induction of apoptosis in NSCLC and, thus, may have a therapeutic use such as a strong apoptosis inducer in cancer cells.

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