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[Quantity of total cell free and cell free fetal DNA in pregnancies with no complications and with preeclampsia].

Authors
  • Lázár, Levente
  • Nagy, Bálint
  • Molvarec, Attila
  • Rigó, János Jr
Type
Published Article
Journal
Orvosi hetilap
Publication Date
May 09, 2010
Volume
151
Issue
19
Pages
784–787
Identifiers
DOI: 10.1556/OH.2010.28784
PMID: 20427261
Source
Medline
License
Unknown

Abstract

The releases of both free fetal and maternal DNA were found to be affected in preeclampsia. Hepatocellular necrosis seems to be responsible - at least partly - for increased circulating total DNA levels in preeclampsia, and the abnormal trophoblast invasion could be responsible for increased trophoblast destruction and elevation of cell free fetal DNA level.

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