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Quantitative immunophenotypic characterization, cryopreservation, and enrichment of second- and third-trimester human fetal cord blood hematopoietic stem cells (progenitor cells).

Authors
  • Surbek, D V
  • Holzgreve, W
  • Jansen, W
  • Heim, D
  • Garritsen, H
  • Nissen, C
  • Wodnar-Filipowicz, A
Type
Published Article
Journal
American Journal of Obstetrics and Gynecology
Publisher
Elsevier
Publication Date
Nov 01, 1998
Volume
179
Issue
5
Pages
1228–1233
Identifiers
PMID: 9822506
Source
Medline
License
Unknown

Abstract

Cord blood stem cell content decreases significantly from the second trimester to term. Cryopreservation and enrichment of these cells from earlier gestational ages is feasible. This might be especially useful for allogeneic stem cell transplantation and for in utero gene therapy.

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