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Quantitative assessment and characterization of visceral hyperalgesia evoked by esophageal balloon distention and acid perfusion in patients with functional heartburn, nonerosive reflux disease, and erosive esophagitis.

Authors
Type
Published Article
Journal
Clinical Journal of Pain
0749-8047
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Volume
26
Issue
4
Pages
326–331
Identifiers
DOI: 10.1097/AJP.0b013e3181c8fc83
PMID: 20393268
Source
Medline
License
Unknown

Abstract

FH patients are more sensitive to mechanical or chemical stimuli than NERD patients. Sensitization of esophageal acid-sensitive chemoreceptors may exert a significant influence on the pressure-sensitive mechanoreceptors, and there is the cooperative interaction in the process of esophageal visceral hyperalgesia.

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