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Quantitative assessment and characterization of visceral hyperalgesia evoked by esophageal balloon distention and acid perfusion in patients with functional heartburn, nonerosive reflux disease, and erosive esophagitis.

Authors
  • Yang, Min
  • Li, Zhao-shen
  • Chen, Dong-feng
  • Zou, Duo-wu
  • Xu, Xiao-rong
  • Fang, Dian-chun
  • Xu, Guo-ming
  • Stephens, R L
  • Wang, Zheng-guo
Type
Published Article
Journal
Clinical Journal of Pain
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
May 01, 2010
Volume
26
Issue
4
Pages
326–331
Identifiers
DOI: 10.1097/AJP.0b013e3181c8fc83
PMID: 20393268
Source
Medline
License
Unknown

Abstract

FH patients are more sensitive to mechanical or chemical stimuli than NERD patients. Sensitization of esophageal acid-sensitive chemoreceptors may exert a significant influence on the pressure-sensitive mechanoreceptors, and there is the cooperative interaction in the process of esophageal visceral hyperalgesia.

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