Affordable Access

deepdyve-link
Publisher Website

QD-filled micelles which combine SPECT and optical imaging with light-induced activation of a platinum(IV) prodrug for anticancer applications.

Authors
  • Maldonado, Carmen R
  • Gómez-Blanco, Nina
  • Jauregui-Osoro, Maite
  • Brunton, Valerie G
  • Yate, Luis
  • Mareque-Rivas, Juan C
Type
Published Article
Journal
Chemical Communications
Publisher
The Royal Society of Chemistry
Publication Date
May 11, 2013
Volume
49
Issue
38
Pages
3985–3987
Identifiers
DOI: 10.1039/c3cc39104c
PMID: 23552819
Source
Medline
License
Unknown

Abstract

The fac-[(99m)Tc(OH2)3(CO)3](+) complex reacts with QD-filled micelles to create a bimodal SPECT-optical imaging probe which upon visible light irradiation generates cisplatin from an inert Pt(IV) prodrug.

Report this publication

Statistics

Seen <100 times