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Pyruvate kinase deficiency in a Somali cat in Australia.

Authors
  • Mansfield, C S
  • Clark, P
Type
Published Article
Journal
Australian veterinary journal
Publication Date
Aug 01, 2005
Volume
83
Issue
8
Pages
483–485
Identifiers
PMID: 16119420
Source
Medline
License
Unknown

Abstract

A 7-year-old neutered male Somali cat, bred in Western Australia, was presented for investigation of jaundice and severe anaemia. Splenomegaly and hepatomegaly were evident on physical examination. Severe anaemia, along with leukopenia and increased liver enzymes, were present on laboratory evaluation. Clinical investigation identified cholangitis and treatment for this resolved the jaundice but failed to resolve the anaemia. Treatment for Mycoplamsa haemofelis was administered concurrently. Genetic testing was then performed and pyruvate kinase deficiency was identified, the first time this has been reported in an Australian cat. Treatment with immunosuppressive medication was not successful.

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