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Pyridoxal phosphate prevents progression of diabetic nephropathy.

Authors
  • Nakamura, Sakurako
  • Li, Hongyan
  • Adijiang, Ayinuer
  • Pischetsrieder, Monika
  • Niwa, Toshimitsu
Type
Published Article
Journal
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Publication Date
Aug 01, 2007
Volume
22
Issue
8
Pages
2165–2174
Identifiers
PMID: 17449494
Source
Medline
License
Unknown

Abstract

PLP prevented progression of nephropathy in STZ-induced diabetic rats by inhibiting formation of AGEs. PLP is considered a promising active form of vitamin B6 for the treatment of AGE-linked disorders such as diabetic nephropathy.

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