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Purulent pericarditis in a patient with rheumatoid arthritis treated with etanercept and methotrexate.

Authors
  • Sweet, David D
  • Isac, George
  • Morrison, Bruce
  • Fenwick, John
  • Dhingra, Vinay
Type
Published Article
Journal
CJEM
Publication Date
Jan 01, 2007
Volume
9
Issue
1
Pages
40–42
Identifiers
PMID: 17391602
Source
Medline
License
Unknown

Abstract

Purulent pericarditis is rarely seen in this post-antibiotic era. We report a case of spontaneous purulent pericarditis in a patient with rheumatoid arthritis being treated with etanercept, a tumour necrosis factor-alpha (TNF-alpha) antagonist, and methotrexate, an immunosuppressant. Both are disease-modifying anti-rheumatic drugs. We discuss the pathophysiology of purulent pericarditis and the recent literature on the infectious complications of TNF-alpha antagonists.

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