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Purification and some properties of malarial pigment.

Authors
  • Homewood, C A
  • Moore, G A
  • Wwarhurst, D C
  • Atkinson, E M
Type
Published Article
Journal
Annals of tropical medicine and parasitology
Publication Date
Sep 01, 1975
Volume
69
Issue
3
Pages
283–287
Identifiers
PMID: 1098588
Source
Medline
License
Unknown

Abstract

Malarial pigment from erythrocytes infected with Plasmodium berghei was purified by treatment with sodium dodecyl sulphate solution, followed by incubation with Pancreatin. The purified pigment retained the apparently crystalline form of pigment within the parasite, rotated polarised light and had the same solubility characterisation as crude malarial pigment. It contained about 1% iron, all of which could be accounted for in terms of haemin. The iron of the pigment molecule is oxidised by the parasite to the ferric state.

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