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Pulmonary endocrine cells of Aymara Indians from the Bolivian Andes.

Authors
  • Williams, D
  • Heath, D
  • Gosney, J
  • Rios-Dalenz, J
Type
Published Article
Journal
Thorax
Publication Date
Jan 01, 1993
Volume
48
Issue
1
Pages
52–56
Identifiers
PMID: 8434355
Source
Medline
License
Unknown

Abstract

If chronic hypoxia as such exerts an influence on human pulmonary endocrine cells it was not apparent in this morphological study. There was no increase in gastrin releasing peptide containing pulmonary endocrine cells, such as have previously been seen in patients with pulmonary hypertension characterised by plexogenic pulmonary arteriopathy. This may be due to the fact that in plexogenic pulmonary arteriopathy there is free migration of smooth muscle cells. Although three of the highlanders in this present study showed pulmonary vascular remodelling, this was in contrast only modest.

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