Chronic headache is caused by several reasons, such as medication over use, psychological stress, depression, anxiety and psychiatric disease. It is often difficult to treat medication over use headache. So it is important to manage the psychological factor before abuse. There are the relationships in migraine and psychiatric disease, especially major depression and panic disorder. In the treatment for chronic headache, it is necessary to assess the personal profile. The Hospital Anxiety and Depression Scale is useful for assess depression and anxiety in patients with painful symptoms.