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Psychopathology in epilepsy: how great is the risk?

Authors
Type
Published Article
Journal
Biological Psychiatry
0006-3223
Publisher
Elsevier
Publication Date
Volume
19
Issue
2
Pages
213–236
Identifiers
PMID: 6370321
Source
Medline

Abstract

The relationship between epilepsy and psychiatric disorder in general and the relationship between epilepsy and psychosis in particular remain controversial issues of long standing. In order to reexamine these central issues concerned with epilepsy/psychopathology relationships, we utilized a Minnesota Multiphasic Personality Inventory (MMPI) sequential diagnostic system to reanalyze 87 published MMPI profiles of patients with epilepsy, other neurological disorders, and chronic physical illnesses encompassing a total of 2786 patients. We found that overall rates of psychopathology were not increased in epilepsy. However, when psychopathology was present, the level of psychosis was greatest in patients with epilepsy. The results are related to the larger literature concerned with the relationship between epilepsy and psychopathology.

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