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Proxy assessment of quality of life in pediatric clinical trials: application of the Health Utilities Index 3.

Authors
Type
Published Article
Journal
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Publication Date
Volume
14
Issue
4
Pages
1045–1056
Identifiers
PMID: 16041900
Source
Medline
License
Unknown

Abstract

Use of the provider proxy-assessed HUI3 in pediatric cancer trials may result in a high proportion of missing data. Trials may benefit more from the use of HRQL measures that consider the acuity of the child's illness, domains specific and sensitive to both disease and treatment, and items that can be proxy-assessed independent of input from parent or patient. Evaluations that combine child self-reports with both parent and provider reports may ultimately provide the most reliable and comprehensive perspective on children's quality of life.

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