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Proteinase inhibitory activity in the plasma of a mollusc: evidence for the presence of alpha-macroglobulin in Biomphalaria glabrata.

Authors
  • Bender, R C
  • Fryer, S E
  • Bayne, C J
Type
Published Article
Journal
Comparative biochemistry and physiology. B, Comparative biochemistry
Publication Date
Aug 01, 1992
Volume
102
Issue
4
Pages
821–824
Identifiers
PMID: 1382916
Source
Medline
License
Unknown

Abstract

1. A methylamine-sensitive inhibitor was present in the plasma of B. glabrata. 2. This inhibitor decreased trypsin activity against a protein substrate, however trypsin retained activity against a low molecular weight substrate in the presence of the inhibitor. 3. Snail plasma protected trypsin from inhibition by soybean trypsin inhibitor. 4. The results give evidence for an alpha-macroglobulin proteinase inhibitor in the plasma of this gastropod mollusc.

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