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Protein kinases A and C stimulate the Na+ active transport in frog skeletal muscle without an appreciable change in the number of sarcolemmal Na+ pumps.

Authors
  • Venosa, R A
Type
Published Article
Journal
Acta physiologica Scandinavica
Publication Date
Dec 01, 2005
Volume
185
Issue
4
Pages
329–334
Identifiers
PMID: 16266374
Source
Medline
License
Unknown

Abstract

It is concluded that in frog skeletal muscle fibres, (1) activation of both PKA and PKC stimulate the Na+ pump by increasing its rate of ionic translocation; and (2) two modes of Na+ active transport (with and without an increase in the number of pumps) are operative, and can be at work simultaneously, a phenomenon to be reckoned with.

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