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Prostate Health Index density improves detection of clinically significant prostate cancer.

Authors
  • Tosoian, Jeffrey J1
  • Druskin, Sasha C1
  • Andreas, Darian1, 2
  • Mullane, Patrick1
  • Chappidi, Meera1
  • Joo, Sarah1
  • Ghabili, Kamyar1
  • Mamawala, Mufaddal1
  • Agostino, Joseph1
  • Carter, Herbert B1
  • Partin, Alan W1
  • Sokoll, Lori J1, 3, 4
  • Ross, Ashley E1, 3, 4
  • 1 Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • 2 Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
  • 3 Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • 4 Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Type
Published Article
Journal
British Journal of Urology
Publisher
Wiley (Blackwell Publishing)
Publication Date
Dec 01, 2017
Volume
120
Issue
6
Pages
793–798
Identifiers
DOI: 10.1111/bju.13762
PMID: 28058757
Source
Medline
Keywords
License
Unknown

Abstract

Based on the present prospective single-centre experience, PHI density could be used to avoid 38% of unnecessary biopsies, while failing to detect only 2% of clinically significant cancers.

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