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A prospective study of triglyceride level, low-density lipoprotein particle diameter, and risk of myocardial infarction.

Authors
  • Stampfer, M J
  • Krauss, R M
  • Ma, J
  • Blanche, P J
  • Holl, L G
  • Sacks, F M
  • Hennekens, C H
Type
Published Article
Journal
JAMA
Publication Date
Sep 18, 1996
Volume
276
Issue
11
Pages
882–888
Identifiers
PMID: 8782637
Source
Medline
License
Unknown

Abstract

These findings indicate that nonfasting triglyceride levels appear to be a strong and independent predictor of future risk of MI, particularly when the total cholesterol level is also elevated. In contrast, LDL particle diameter is associated with risk of MI, but not after adjustment for triglyceride level. Increased triglyceride level, small LDL particle diameter, and decreased HDL-C levels appear to reflect underlying metabolic perturbations with adverse consequences for risk of MI; elevated triglyceride levels may help identify high-risk individuals.

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