Affordable Access

Propylthiouracil and carbimazole associated-antineutrophil cytoplasmic antibodies (ANCA) in patients with Graves' disease.

Authors
Type
Published Article
Journal
Clinical endocrinology
Publication Date
Volume
60
Issue
6
Pages
671–675
Identifiers
PMID: 15163328
Source
Medline
License
Unknown

Abstract

This study revealed a high prevalence of ANCA in treated patients with Graves' disease but not in those with Hashimoto's thyroiditis. Furthermore, within the Graves' disease population, ANCA development was associated with propylthiouracil usage to a greater extent than carbimazole. These findings suggest that the altered immune environment associated with autoimmune thyroid disease is not sufficient to develop ANCA but treatment with thionamides is important in promoting ANCA development.

Statistics

Seen <100 times