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Prophylactic antibiotics in vaginal and abdominal hysterectomy.

Authors
  • Jennings, R H
Type
Published Article
Journal
Southern medical journal
Publication Date
Mar 01, 1978
Volume
71
Issue
3
Pages
251–254
Identifiers
PMID: 343256
Source
Medline
License
Unknown

Abstract

A double-blind, prospective study over a 12-month period evaluated the effectiveness of cefazolin and cephalexin in reducing infection and morbidity in private patients undergoing vaginal and abdominal hysterectomy. Prophylactic antibiotics reduced febrile morbidity from 74.4% to 20.8% in the vaginal group and from 46.2% to 24.0% in the abdominal group. Serious postoperative infections such as pelvic abscess, pelvic cellulitis and abdominal wound infection were reduced from 11.5% to 0% in the abdominal group and from 32.6% to 2.1% in the vaginal group. The use of prophylactic antibiotics was of benefit in the perimenopausal and postmenopausal patient, as well as in the premenopausal patient, although, in some categories, the numbers were too small to be statistically significant.

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