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[The prooxidant system. Approaches to the choice of research algorithm].

Authors
  • Pluzhnikov, N N
  • Bakulina, L S
  • Kozlov, O S
  • Iartsev, A I
Type
Published Article
Journal
Vestnik otorinolaringologii
Publication Date
Jan 01, 2010
Issue
5
Pages
72–75
Identifiers
PMID: 21207902
Source
Medline
License
Unknown

Abstract

The regulatory function of the processes involving free radicals known to maintain cellular vital activity and their role as an intermediate stage of many vitally important enzymatic reactions attract the attention of researchers interested in the mechanisms of production and inactivation of free radicals. Investigations into prooxidant and antioxidant systems along with evaluation of the intensity of free-radical oxidation make it possible to resolve many problems including elucidation of dynamic activity of pathological process, prognosis of various pathological conditions, and the choice of possible methods for the correction of prooxidant/antioxidant balance in patients with ENT diseases. The development of algorithms and methods for the assessment of parameters of activity of the prooxidant system allows for their stage by stage measurement and evaluation.

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