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Prolyl hydroxylase domain protein 2 plays a critical role in diet-induced obesity and glucose intolerance.

Authors
  • Matsuura, Hirohide
  • Ichiki, Toshihiro
  • Inoue, Eriko
  • Nomura, Masatoshi
  • Miyazaki, Ryohei
  • Hashimoto, Toru
  • Ikeda, Jiro
  • Takayanagi, Ryoichi
  • Fong, Guo-Hua
  • Sunagawa, Kenji
Type
Published Article
Journal
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Publication Date
May 28, 2013
Volume
127
Issue
21
Pages
2078–2087
Identifiers
DOI: 10.1161/CIRCULATIONAHA.113.001742
PMID: 23630130
Source
Medline
Keywords
License
Unknown

Abstract

PHD2 in adipose tissue plays a critical role in the development of diet-induced obesity and glucose intolerance. PHD2 might be a novel target molecule for the treatment of obesity and associated metabolic abnormalities.

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