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Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review

Authors
  • Su, Yana
  • Cui, Li
  • Zhu, Mingqin
  • Liang, Yixuan
  • Zhang, Ying
Type
Published Article
Journal
Frontiers in Neurology
Publisher
Frontiers Media SA
Publication Date
Sep 18, 2020
Volume
11
Identifiers
DOI: 10.3389/fneur.2020.01017
PMID: 33071929
PMCID: PMC7533529
Source
PubMed Central
Keywords
License
Unknown

Abstract

Progressive encephalomyelitis with rigidity and myoclonus (PERM) is part of the variant type of the Stiff Person Syndrome (SPS) and is a rare neurological disease. We report here a patient with PERM who had thymoma and was positive for anti-glutamic acid decarboxylase (anti-GAD) antibodies. Her symptoms improved after treatment with hormones and gamma globulin. We also summarized the literature review of patients with PERM accompanied by tumors reported.

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