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[Prognostic factors in prostate cancer].

Authors
  • Bonkhoff, H
Type
Published Article
Journal
Der Pathologe
Publication Date
Nov 01, 2005
Volume
26
Issue
6
Pages
433–443
Identifiers
PMID: 16205900
Source
Medline
License
Unknown

Abstract

Since several therapeutic options are currently available for clinically organ-confined prostate cancer, morphological parameters have rapidly emerged as prognostic factors to stratify patients into different therapeutic modalities. In addition to the PSA value, pathologic stage, as defined by the TNM system, Gleason grade and the surgical margin status, other markers have prognostic implications. This includes the percent pattern 4/5 cancer, tumor volume, intraductal spread, large volume perineural invasion and molecular markers. This review discusses the methods of sampling and reporting in prostate pathology with an emphasis on well established and new prognostic factors.

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