Production of Camptothecin from Nothapodytes nimmoniana: An Overview

Affordable Access

Download Read

Production of Camptothecin from Nothapodytes nimmoniana: An Overview

Authors
Type
Published Article
Journal
International Journal of Life-Sciences Scientific Research
Publisher
Marwah Infotech
Publication Date
Nov 17, 2017
Volume
3
Issue
6
Pages
1476–1483
Identifiers
DOI: 10.21276/ijlssr.2017.3.6.9
Source
MyScienceWork
License
Green

Abstract

Nothapodytes nimmoniana is an endangered tree endemic to Western Ghats, India and it is the convenient source for large scale isolation of camptothecin (CPT). Since the first report of CPT detection in N. nimmoniana, significant work has been done on its applications. Due to heavy collection of its wood chips for CPT, population is under threat in India. Several plant tissue culture techniques offer alternative strategies for clonal propagation and CPT production to conserve the species. Various strategies are employed to enhance in vitro condition response through culture medium optimization, elicitation, and artificial seed method. In this article, we have reviewed progress made so far on different methods of plant tissue culture techniques for production of camptothecin from N. nimmoniana and biosynthesis of CPT in details.

Report this publication

Statistics

Seen <100 times
Downloaded <100 times