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Processing of the major pancreatic zymogen granule membrane protein, GP2.

Authors
  • Fritz, Benjamin A
  • Poppel, Clinton S
  • Fei, Matthew W
  • Lowe, Anson W
Type
Published Article
Journal
Pancreas
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
May 01, 2002
Volume
24
Issue
4
Pages
336–343
Identifiers
PMID: 11961485
Source
Medline
License
Unknown

Abstract

In contrast to other digestive enzymes secreted by the pancreas that are activated by proteolysis in the intestine, GP2 undergoes sequential intracellular cleavage. Alterations in GP2 structure by proteolysis may regulate GP2 function at specific sites within the pancreatic cell.

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