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Procainamide-induced agranulocytosis and thrombocytopenia.

Authors
  • Rothman, I K
  • Amorosi, E L
Type
Published Article
Journal
Archives of Internal Medicine
Publisher
American Medical Association
Publication Date
Feb 01, 1979
Volume
139
Issue
2
Pages
246–247
Identifiers
PMID: 434983
Source
Medline
License
Unknown

Abstract

Procainamide therapy has frequently been reported as a cause of agranulocytosis, but severe thrombocytopenia associated with the use of this drug has been noted only once. We report a case of simultaneously occurring agranulocytosis and profound thrombocytopenia in a patient receiving procainamide hydrochloride. Different mechanisms appeared to be responsible for the two cytopenias.

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