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Primary Cutaneous B-Cell Lymphomas

Authors
  • Al-Katib, Ayad M
  • Mohamed, Anwar N
Publication Date
Feb 25, 2020
Source
I-Revues
Keywords
Language
English
License
Unknown
External links

Abstract

Primary cutaneous B-cell lymphomas (PCBCL) are a heterogeneous group of mature B-cells neoplasms that present in the skin without evidence of nodal or systemic involvement. The clinical and pathologic features of PCBCL differ significantly from the equivalent nodal lymphomas. Three main subtypes of PCBCL are recognized by the 2016 revised WHO classification. Studies have shown that PCBCLs are characterized by distinct immunophenotypic features, chromosomal aberrations and gene rearrangements which provide further support for their classification as separate entities from their nodal types.

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