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Priapism from quetiapine overdose: first report and proposal of mechanism.

Authors
  • Pais, V M
  • Ayvazian, P J
Type
Published Article
Journal
Urology
Publisher
Elsevier
Publication Date
Sep 01, 2001
Volume
58
Issue
3
Pages
462–462
Identifiers
PMID: 11549503
Source
Medline
License
Unknown

Abstract

We report a case of priapism occurring after an overdose of the newly approved atypical antipsychotic quetiapine. A review of its previously published receptor-binding studies suggests that alpha-adrenergic blockade may be the responsible mechanism. To our knowledge, this is the first report of priapism associated with quetiapine, and we recommend the inclusion of priapism in its list of potential adverse effects in cases of overdose.

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