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Prevention of pulmonary emboli in a respiratory intensive care unit: efficacy of low-dose heparin.

Authors
  • Pingleton, S K
  • Bone, R C
  • Pingleton, W W
  • Ruth, W E
Type
Published Article
Journal
Chest
Publication Date
Jun 01, 1981
Volume
79
Issue
6
Pages
647–650
Identifiers
PMID: 6971738
Source
Medline
License
Unknown

Abstract

Ninety-eight patients admitted to our respiratory intensive care unit during a one-year period were compared retrospectively with 99 well-matched patients admitted during a second one-year period. The use of prophylactic low-dose heparin in the second year was associated with a significant decrease in pulmonary emboli documented by ventilation-perfusion scan, pulmonary angiography, and autopsy. No specific bleeding complications could be directly attributed to the use of low-dose heparin. The frequency and severity of gastrointestinal hemorrhage as determined by hemoglobin fall and transfusion requirements were not significantly affected by the prophylactic use of low-dose heparin. Low-dose heparin appears to be effective and safe in respiratory intensive care unit patients in the prevention of pulmonary emboli.

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