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Prevalence of the myosin-binding protein C mutation in Maine Coon cats.

Authors
  • Fries, R
  • Heaney, A M
  • Meurs, K M
Type
Published Article
Journal
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine
Publication Date
Jan 01, 2008
Volume
22
Issue
4
Pages
893–896
Identifiers
DOI: 10.1111/j.1939-1676.2008.0113.x
PMID: 18498321
Source
Medline
License
Unknown

Abstract

The prevalence of the mutation (heterozygous or homozygous) was very similar among countries of submission, suggesting that the 34% mutation rate of the tested samples is a reasonable estimate of the true prevalence of the mutation within the breed. Because of the high prevalence of this mutation, a breeding recommendation to eliminate all cats with the mutation could have a substantial impact on the gene pool. Additional studies are indicated to explore the relationship between genotype and clinical outcome in affected cats.

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