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Prevalence of mixed cryoglobulins in relation to CD4 cell count among patients coinfected with HIV and hepatitis C virus.

Authors
  • Aaron, Laurent
  • Lebray, Pascal
  • Alyanakian, Marie-Alexandra
  • Roudière, Laurent
  • Therby, Audrey
  • Chaix, Marie-Laure
  • Dupont, Bertrand
  • Pol, Stanislas
  • Viard, Jean-Paul
Type
Published Article
Journal
Clinical Infectious Diseases
Publisher
Oxford University Press
Publication Date
Jan 15, 2005
Volume
40
Issue
2
Pages
306–308
Identifiers
PMID: 15655752
Source
Medline
License
Unknown

Abstract

Cryoglobulinemia was studied in human immunodeficiency virus-positive, hepatitis C virus (HCV)-positive patients in relation to their CD4 cell count. Cryoglobulinemia was found in 18 (31.6%) of 57 patients: 17 (44.7%) of 38 patients with a CD4 cell count of >or=200 cells/ micro L versus 1 (5.3%) of 19 patients with a CD4 cell count of <200 cells/ micro L (P=.0064). Cell-mediated immunity could, therefore, contribute to the production of HCV-associated cryoglobulins.

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