The incidence of coronary heart disease (CHD) was determined, on the basis of extended Minnesota code criteria, in a Siberian population of northern Khanty of both sexes, aged 19 to 69 years (a total of 721 people). CHD prevalence by age was 34 +/- 3% in males and 24 +/- 2% in females. CHD prevalence in males below 40 showed no significant relation with any of the major risk factors, while a positive correlation with hypercholesterolemia and hypo-alpha-cholesterolemia was noted in people of older age. Females of different age showed a negative correlation with arterial hypertension, and a positive correlation with hypercholesterolemia and hypertriglyceridemia. Excessive body weight is not a CHD risk factor for the Khanty.