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[Prevalence of dyslipoproteinemias among diabetes mellitus patients].

Authors
Type
Published Article
Journal
Problemy e̊ndokrinologii
Publication Date
Volume
33
Issue
2
Pages
13–16
Identifiers
PMID: 3601885
Source
Medline
License
Unknown

Abstract

The blood levels of total cholesterol, triglycerides, HDL cholesterol were determined in 330 patients with Type I and II diabetes mellitus (DM) and in 400 persons with the normal glucose tolerance test (GTT). On a curve of the distribution of values of total cholesterol, triglycerides, HDL cholesterol the upper 10% values were regarded as hypercholesterinemia (HCS) and hypertriglyceridemia (HTG) and the lower 10% values as hypo-alpha-cholesterinemia (hypo-alpha-CS). The prevalence of dyslipoproteinemia was shown to be much higher in the DM patients than in the healthy persons resulting from a more frequent development of HCS, HTG and hypo-alpha-CS in the patients. Some peculiarities of the prevalence of dyslipoproteinemia with relation to a DM type were revealed. It was shown that in Type I DM the prevalence of HCS and HTG was much higher than that in the persons with the normal GTT whereas the frequency of hypo-alpha-CS in both groups was the same. In patients with Type II DM as compared to the control group not only HCS and HTG but also hypo-alpha-CS were much more frequent. Moreover, the prevalence of HTG and hypo-alpha-CS in Type II DM was much higher than in Type I DM. Since dyslipoproteinemias were a risk factor in the development of atherosclerosis and coronary heart disease, one might assume that their greater prevalence among DM patients would determine patients' greater predisposition to atherosclerosis.(ABSTRACT TRUNCATED AT 250 WORDS)

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