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The presence in human tumours of a Mr 11,700 calcium-binding protein similar to rodent oncomodulin.

Authors
  • MacManus, J P
  • Whitfield, J F
  • Stewart, D J
Type
Published Article
Journal
Cancer Letters
Publisher
Elsevier
Publication Date
Jan 01, 1984
Volume
21
Issue
3
Pages
309–315
Identifiers
PMID: 6692349
Source
Medline
Language
English
License
Unknown

Abstract

Oncomodulin is a parvalbumin-like calcium binding protein of Mr 11,700 from rodent tumours. An antiserum to rat oncomodulin cross-reacts with extracts of several human solid tumour tissues. When purified, this human immunoreactive protein binds calcium, and has a molecular weight and amino acid composition similar to the rodent protein. This protein was not found in normal adult human tissue.

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