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Preparation of J-aggregate liposome dispersions and their chromic transformation.

Authors
  • Kato, Noritaka
  • Prime, Jennifer
  • Katagiri, Kiyofumi
  • Caruso, Frank
Type
Published Article
Journal
Langmuir : the ACS journal of surfaces and colloids
Publication Date
Jul 06, 2004
Volume
20
Issue
14
Pages
5718–5723
Identifiers
PMID: 16459584
Source
Medline
License
Unknown

Abstract

We report the preparation of aqueous liposome dispersions of J-aggregates formed by the amphiphilic merocyanine dye (MD). A series of liposome-forming lipids were dispersed together with MD J-aggregates at different molar ratios of MD to lipid. The MD J-aggregate dispersions prepared with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) at the MD to DMPC ratio of 0.16 exhibit good dispersibility; that is, they can be readily redispersed without any flocculation even after their precipitation. By use of different counterions for the MD molecules, two types of J-aggregate dispersions, one that exhibits an absorption band (J-band) at 635 nm (type I) and the other at 600 nm (type II), were obtained. As an example of the use of MD J-aggregates liposome dispersions, the thermochromic transformation of MD J-aggregates was demonstrated. When the dispersions are heated, J-aggregates of type I transformed into type II at a certain temperature (T(disp)). The parameters that control the speed of the transformation and the value of T(disp) were determined.

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