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Preparation of alpha-keto ester enol acetates as potential prodrugs of human neutrophil elastase inhibitors.

Authors
  • Burkhart, J P
  • Mehdi, S
  • Koehl, J R
  • Angelastro, M R
  • Bey, P
  • Peet, N P
Type
Published Article
Journal
Bioorganic & Medicinal Chemistry Letters
Publisher
Elsevier
Publication Date
Jan 06, 1998
Volume
8
Issue
1
Pages
63–64
Identifiers
PMID: 9871629
Source
Medline
License
Unknown

Abstract

Enol acetates of a-keto esters with E configuration were prepared as potential prodrugs for human neutrophil elastase (HNE) inhibitors.

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