Affordable Access

deepdyve-link
Publisher Website

Prenatal sonographic diagnosis of premature constriction of the fetal ductus arteriosus after maternal self-medication with benzydamine hydrochloride: report of 3 cases and review of the literature.

Authors
  • Krzeszowski, Waldemar1
  • Wilczyński, Jan1
  • Grzesiak, Mariusz1
  • Nowakowska, Dorota2
  • 1 Third Chair of Gynecology and Obstetrics, Department of Fetal-Maternal Medicine and Gynecology, Medical University, Lodz, Poland. , (Poland)
  • 2 Third Chair of Gynecology and Obstetrics, Department of Fetal-Maternal Medicine and Gynecology, Medical University, Lodz, Poland. [email protected] , (Poland)
Type
Published Article
Journal
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Publication Date
Mar 01, 2015
Volume
34
Issue
3
Pages
531–535
Identifiers
DOI: 10.7863/ultra.34.3.531
PMID: 25715374
Source
Medline
Keywords
License
Unknown

Abstract

We report 3 cases of prenatal diagnosis of premature constriction of the ductus arteriosus after maternal benzydamine hydrochloride therapy (3-mg lozenges) in third-trimester pregnancies. In each case, fetal echocardiography revealed a dilated, hypocontractile right ventricle with severe tricuspid regurgitation and constriction of the ductus arteriosus. Although the effect of indomethacin and other nonsteroidal anti-inflammatory drugs on prenatal ductal constriction is well known, readily available over-the-counter nonsteroidal anti-inflammatory drugs such as benzydamine can have an equally deleterious effect and are best avoided in the third trimester of pregnancy.

Report this publication

Statistics

Seen <100 times