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Prenatal exposure to polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) may influence birth weight among infants in a Swedish cohort with background exposure: a cross-sectional study.

Authors
  • Lignell, Sanna1
  • Aune, Marie
  • Darnerud, Per Ola
  • Hanberg, Annika
  • Larsson, Susanna C
  • Glynn, Anders
  • 1 Risk Benefit Assessment Department, National Food Agency, Box 622, Uppsala SE-751 26, Sweden. [email protected] , (Sweden)
Type
Published Article
Journal
Environmental health : a global access science source
Publication Date
May 31, 2013
Volume
12
Pages
44–44
Identifiers
DOI: 10.1186/1476-069X-12-44
PMID: 23724965
Source
Medline
License
Unknown

Abstract

Our results indicate that prenatal exposure to di-ortho PCBs and PBDE(4) may influence birth weight in different directions, i.e. PCB exposure was associated with higher birth weight and PBDE exposure with lower birth weight. Maternal pre-pregnancy BMI and weight gain during pregnancy were important confounders that may hide positive association between di-ortho PCB exposure and birth weight if they are not included in the statistical model. We speculate that even small PCB- and PBDE-induced shifts in the distribution of birth weight may influence future public health in populations with background exposure.

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