Premature menarche--a legend or a defined clinical syndrome.
Department of Pediatric Endocrinology, Institute of Endocrinology, Medical Academy of Lódź.
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The properness of diagnosing the premature menarche as isolated clinical syndrome is often questioned. A long-term observation od 2 girls with premature menarche has been described. A discussion is presented about the role of imbalance within the hypothalamus-pituitary-gonads axis and the role of disturbances in peripheral responsiveness to sex hormones in the patho-mechanism of premature menarche.
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This record was last updated on 07/07/2017 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/1345369