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Premature menarche--a legend or a defined clinical syndrome.

Authors
  • 1
Type
Published Article
Journal
Endokrynologia Polska
Publication Date
Volume
43
Issue
4
Pages
475–479
Identifiers
PMID: 1345369
Source
Medline

Abstract

The properness of diagnosing the premature menarche as isolated clinical syndrome is often questioned. A long-term observation od 2 girls with premature menarche has been described. A discussion is presented about the role of imbalance within the hypothalamus-pituitary-gonads axis and the role of disturbances in peripheral responsiveness to sex hormones in the patho-mechanism of premature menarche.

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