Affordable Access

Publisher Website

Predictors of attempted suicide among youth living with perinatal HIV infection and perinatal HIV exposed uninfected counterparts.

  • Kreniske, Philip1
  • Mellins, Claude Ann
  • Dolezal, Curtis
  • Morrison, Corey
  • Shea, Eileen
  • Fisher, Prudence W
  • Kluisza, Luke
  • Robbins, Reuben N
  • Nguyen, Nadia
  • Leu, Cheng-Shiun
  • Wiznia, Andrew
  • Abrams, Elaine J
  • 1 HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University Department of Psychiatry, Mental Health Data Science, Columbia University Medical Center, New York, NY Child and Adolescent Psychiatry, New York State Psychiatric Institute and Columbia University Department of Biostatistics, Mailman School of Public Health, Columbia University, NY, USA Jacobi Medical Center, Albert Einstein College of Medicine ICAP at Columbia University, Mailman School of Public Health and Vagelos College of Physicians & Surgeons, Columbia University.
Published Article
Journal of acquired immune deficiency syndromes (1999)
Publication Date
Aug 16, 2021
DOI: 10.1097/QAI.0000000000002784
PMID: 34406984


Suicide is a leading cause of death among adolescents and young adults (AYA). AYA living with perinatally-acquired HIV infection (AYALPHIV) are at higher risk of attempted suicide as compared to AYA who were perinatally HIV-exposed but uninfected (AYAPHEU). To inform interventions we identified risk and protective factors for attempted suicide among AYALPHIV and AYAPHEU. Data come from a longitudinal New York City-based study of AYALPHIV and AYAPHEU (n=339; enrollment age 9-16 years) interviewed approximately every 12-18 months. Our main outcome was suicide attempt at any follow-up. The DISC was used to assess psychiatric disorder diagnoses and attempted suicide and the Child Depression Inventory (CDI) to assess depression symptoms. Psychosocial and sociodemographic risk factors were also measured. Analyses employed backward stepwise logistic regression modeling. At enrollment, 51% were female, 49% Black, 40% Latinx, and 11% both Black and Latinx. Attempted suicide prevalence was significantly higher among AYALPHIV compared to AYAPHEU (27% vs 16%, p = 0.019) with AYALPHIV having 2.21 times the odds of making an attempt (95% CI: [1.18, 4.12], p = 0.013). Higher CDI scores were associated with an increased risk of attempted suicide in both groups and the total sample. The presence of DISC-defined behavior disorder increased risk of attempted suicide in the total sample and the AYALPHIV sub-group. Religiosity was protective of attempted suicide in AYALPHIV. AYALPHIV had increased suicide attempts compared to AYAPHEU. Religiosity was protective in AYALPHIV. Highlighting a need for prevention early mental health challenges were associated with risk. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Report this publication


Seen <100 times