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Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase protein expression on survival in adjuvantly treated stage III colon cancer patients.

Authors
  • Westra, J L
  • Hollema, H
  • Schaapveld, M
  • Platteel, I
  • Oien, K A
  • Keith, W N
  • Mauritz, R
  • Peters, G J
  • Buys, C H C M
  • Hofstra, R M W
  • Plukker, J Th M
Type
Published Article
Journal
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO
Publication Date
Oct 01, 2005
Volume
16
Issue
10
Pages
1646–1653
Identifiers
PMID: 16012177
Source
Medline
License
Unknown

Abstract

Expression of TS and DPD proteins is not predictive for survival in patients with stage III colon cancer treated adjuvantly with 5-FU regimens. TS protein levels did not alter the effect of TP 53 mutation status.

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