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Prediction of pathological stage and clinical outcome in prostate cancer: an improved pre-operative model incorporating biopsy-determined intraductal carcinoma.

Authors
  • Cohen, R J
  • Chan, W C
  • Edgar, S G
  • Robinson, E
  • Dodd, N
  • Hoscek, S
  • Mundy, I P
Type
Published Article
Journal
British journal of urology
Publication Date
Mar 01, 1998
Volume
81
Issue
3
Pages
413–418
Identifiers
PMID: 9523662
Source
Medline
License
Unknown

Abstract

The model which best predicted pathological stage and clinical outcome involved first identifying those cancers with IDC-P as having the poorest outcome. Cancers without IDC-P were then separated into low- and high-risk groups on the basis of serum PSA levels below and above 10 ng/mL, and those in the high-risk group further stratified using Gleason grading. Furthermore, the use of a sequential consideration of pre-operative variables including IDC-P allowed cases to be grouped which, after radical surgery, closely correlated with clinical outcome.

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