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Prediction of outcome by early response in childhood acute lymphoblastic leukemia.

Authors
  • Möricke, A
  • Lauten, M
  • Beier, R
  • Odenwald, E
  • Stanulla, M
  • Zimmermann, M
  • Attarbaschi, A
  • Niggli, F
  • Schrappe, M
Type
Published Article
Journal
Klinische Pädiatrie
Publisher
Georg Thieme Verlag KG
Publication Date
May 01, 2013
Volume
225 Suppl 1
Identifiers
DOI: 10.1055/s-0033-1337964
PMID: 23700057
Source
Medline
License
Unknown

Abstract

Selective addition of day 15 marrow response to conventional stratification criteria applied on ALL-BFM 95 may significantly improve risk-adapted treatment delivery. Even though cutting-edge trial risk stratification is meanwhile dominated by minimal residual disease evaluation, an improved conventional risk assessment, as presented here, could be of great importance to countries lacking the technical and/or financial resources associated with the application of minimal residual disease analysis.

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