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Predicting childhood overweight and obesity using maternal and early life risk factors: a systematic review.

Authors
  • Ziauddeen, N1
  • Roderick, P J1
  • Macklon, N S2
  • Alwan, N A1
  • 1 Academic Unit of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • 2 Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
Type
Published Article
Journal
Obesity reviews : an official journal of the International Association for the Study of Obesity
Publication Date
Mar 01, 2018
Volume
19
Issue
3
Pages
302–312
Identifiers
DOI: 10.1111/obr.12640
PMID: 29266702
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Childhood obesity is a serious public health challenge, and identification of high-risk populations with early intervention to prevent its development is a priority. We aimed to systematically review prediction models for childhood overweight/obesity and critically assess the methodology of their development, validation and reporting. Medline and Embase were searched systematically for studies describing the development and/or validation of a prediction model/score for overweight and obesity between 1 to 13 years of age. Data were extracted using the Cochrane CHARMS checklist for Prognosis Methods. Ten studies were identified that developed (one), developed and validated (seven) or externally validated an existing (two) prediction model. Six out of eight models were developed using automated variable selection methods. Two studies used multiple imputation to handle missing data. From all studies, 30,475 participants were included. Of 25 predictors, only seven were included in more than one model with maternal body mass index, birthweight and gender the most common. Several prediction models exist, but most have not been externally validated or compared with existing models to improve predictive performance. Methodological limitations in model development and validation combined with non-standard reporting restrict the implementation of existing models for the prevention of childhood obesity. © 2017 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation.

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