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PPARγ attenuates intimal hyperplasia by inhibiting TLR4-mediated inflammation in vascular smooth muscle cells.

Authors
  • Zhang, Li-Li
  • Gao, Chang-Yue
  • Fang, Chuan-Qin
  • Wang, Yan-Jiang
  • Gao, Dong
  • Yao, Guo-En
  • Xiang, Jing
  • Wang, Jing-Zhou
  • Li, Jing-Cheng
Type
Published Article
Journal
Cardiovascular Research
Publisher
Oxford University Press
Publication Date
Dec 01, 2011
Volume
92
Issue
3
Pages
484–493
Identifiers
DOI: 10.1093/cvr/cvr238
PMID: 21880694
Source
Medline
License
Unknown

Abstract

PPARγ inhibits vascular smooth muscle cell proliferation and migration by suppressing TLR4-mediated inflammation and ultimately attenuates intimal hyperplasia after carotid injury.

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