Affordable Access

[Potentiation of the acute toxic effects of cocaine by ethyl alcohol].

Authors
Type
Published Article
Journal
Bulletin de l'Académie nationale de médecine
Publication Date
Volume
176
Issue
2
Pages
193–197
Identifiers
PMID: 1633559
Source
Medline
License
Unknown

Abstract

Ethyl alcohol increases significantly the lethality of cocaine intoxication in the rat. This lethality is not modified by nicardipine or flunarizine, antidotes to cocaine, and might be due to the formation of a newly identified active metabolite cocaethylene. In addition alcohol like cocaine inhibits the baro receptor reflex.

Statistics

Seen <100 times