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A potential role for B-cell activating factor in the pathogenesis of autoimmune myasthenia gravis.

Authors
  • Ragheb, Samia
  • Lisak, Robert
  • Lewis, Richard
  • Van Stavern, Gregory
  • Gonzales, Felicitas
  • Simon, Kirk
Type
Published Article
Journal
Archives of Neurology
Publisher
American Medical Association
Publication Date
Oct 01, 2008
Volume
65
Issue
10
Pages
1358–1362
Identifiers
DOI: 10.1001/archneur.65.10.1358
PMID: 18852352
Source
Medline
License
Unknown

Abstract

We report that BAFF levels are increased in patients with autoimmune MG. Our data suggest that BAFF is likely to play a role in the pathogenesis of MG by promoting the survival and maturation of autoreactive B cells.

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