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Potassium cyanate, an in vitro inhibitor of lymphocyte blast transformation without in vivo activity.

Authors
  • Grayzel, A I
  • Roth, E F Jr
  • Beck, C L
Type
Published Article
Journal
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Publication Date
Jun 01, 1976
Volume
152
Issue
2
Pages
139–142
Identifiers
PMID: 132665
Source
Medline
License
Unknown

Abstract

Potassium cyanate (400 mug/ml) inhibited the blastogenesis of lymphocytes in response to PHA and the response of lymphocytes in mixed lymphocyte cultures. Cyanate administered to mice at a dose of 30 mg per kg per day did not delay allograft rejection.

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