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Post-infectious persistent cough: pathogenesis and therapeutic options.

Authors
  • Capristo, Carlo1
  • Rossi, Giovanni A2, 3
  • 1 Department of Woman and Child, General and Specialized Surgery, L. Vanvitelli University of Campania, Naples, Italy. , (Italy)
  • 2 Pulmonology and Allergology Unit, Department of Pediatrics, G. Gaslini Hospital, Genoa, Italy - [email protected] , (Italy)
  • 3 Cystic Fibrosis Regional Center, G. Gaslini Hospital, Genoa, Italy. , (Italy)
Type
Published Article
Journal
Minerva pediatrica
Publication Date
Oct 01, 2017
Volume
69
Issue
5
Pages
444–452
Identifiers
DOI: 10.23736/S0026-4946.17.04958-1
PMID: 28565899
Source
Medline
License
Unknown

Abstract

Post-infectious cough is a common symptom associated with common colds and/or upper respiratory tract infection. This cough is expected to last for only for few days and resolve spontaneously, whilst when persists for longer than three weeks is defined "persistent" and is associated tickling or an irritating sensation in the throat which often leads to paroxysms of coughing. Persistent post-infectious cough can cause morbidity since it may interfere with usual living. Despite the recent advances in understanding the mechanisms that regulate cough, in physiological and pathological conditions, current therapeutic options for post-infectious cough are little or only moderately effective.

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