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A Possible treatment strategy and clinical factors to estimate the treatment response in Bebesia gibsoni infection.

Authors
Type
Published Article
Journal
The Journal of veterinary medical science / the Japanese Society of Veterinary Science
Publication Date
Volume
69
Issue
5
Pages
563–568
Identifiers
PMID: 17551236
Source
Medline
License
Unknown

Abstract

The effectiveness of combination therapy using clindamycin, metronidazole and doxycycline against canine babesiosis, and the usefulness of platelet count and the plasma C-reactive protein (CRP) concentration as an estimation factor for treatment, were evaluated in four dogs experimentally infected with Babesia gibsoni. The combination therapy successfully eliminated B. gibsoni in peripheral blood in 3 of 4 dogs, however the remaining dog showed obvious uncontrolled relapse after a temporary recovery. In addition, it was shown that CRP levels decreased in an inverse relationship to the recovery of packed cell volume and therefore CRP levels could be used as an optional clinical marker to estimate the response to treatment.

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